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Role of mTOR Inhibitors in Kidney Disease

The first compound that inhibited the mammalian target of rapamycin (mTOR), sirolimus (rapamycin) was discovered in the 1970s as a soil bacterium metabolite collected on Easter Island (Rapa Nui). Because sirolimus showed antiproliferative activity, researchers investigated its molecular target and i...

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Detalles Bibliográficos
Autores principales: Kajiwara, Moto, Masuda, Satohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926507/
https://www.ncbi.nlm.nih.gov/pubmed/27338360
http://dx.doi.org/10.3390/ijms17060975