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RNA Secondary Structure Modulates FMRP’s Bi-Functional Role in the MicroRNA Pathway

MicroRNAs act by post-transcriptionally regulating the gene expression of 30%–60% of mammalian genomes. MicroRNAs are key regulators in all cellular processes, though the mechanism by which the cell activates or represses microRNA-mediated translational regulation is poorly understood. In this revie...

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Detalles Bibliográficos
Autores principales: Kenny, Phillip, Ceman, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926514/
https://www.ncbi.nlm.nih.gov/pubmed/27338369
http://dx.doi.org/10.3390/ijms17060985