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The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer

The androgen receptor (AR) is the dominant growth factor in prostate cancer (PCa). Therefore, understanding how ARs regulate the human transcriptome is of paramount importance. The early effects of castration on human PCa have not previously been studied 27 patients medically castrated with degareli...

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Detalles Bibliográficos
Autores principales: Shaw, Greg L., Whitaker, Hayley, Corcoran, Marie, Dunning, Mark J., Luxton, Hayley, Kay, Jonathan, Massie, Charlie E., Miller, Jodi L., Lamb, Alastair D., Ross-Adams, Helen, Russell, Roslin, Nelson, Adam W., Eldridge, Matthew D., Lynch, Andrew G., Ramos-Montoya, Antonio, Mills, Ian G., Taylor, Angela E., Arlt, Wiebke, Shah, Nimish, Warren, Anne Y., Neal, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926724/
https://www.ncbi.nlm.nih.gov/pubmed/26572708
http://dx.doi.org/10.1016/j.eururo.2015.10.042