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Synergistic Increase of Serum BDNF in Alzheimer Patients Treated with Cerebrolysin and Donepezil: Association with Cognitive Improvement in ApoE4 Cases

BACKGROUND: Low circulating brain derived neurotrophic factor may promote cognitive deterioration, but the effects of neurotrophic and combination drug therapies on serum brain derived neurotrophic factor were not previously investigated in Alzheimer’s disease. METHODS: We evaluated the effects of C...

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Detalles Bibliográficos
Autores principales: Alvarez, X. Anton, Alvarez, Irene, Iglesias, Olalla, Crespo, Ignacio, Figueroa, Jesus, Aleixandre, Manuel, Linares, Carlos, Granizo, Elias, Garcia-Fantini, Manuel, Marey, Jose, Masliah, Eliezer, Winter, Stefan, Muresanu, Dafin, Moessler, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926802/
https://www.ncbi.nlm.nih.gov/pubmed/27207906
http://dx.doi.org/10.1093/ijnp/pyw024