Loss of Iroquois homeobox transcription factors 3 and 5 in osteoblasts disrupts cranial mineralization

Cranial malformations are a significant cause of perinatal morbidity and mortality. Iroquois homeobox transcription factors (IRX) are expressed early in bone tissue formation and facilitate patterning and mineralization of the skeleton. Mice lacking Irx5 appear grossly normal, suggesting that redund...

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Detalles Bibliográficos
Autores principales: Cain, Corey J., Gaborit, Nathalie, Lwin, Wint, Barruet, Emilie, Ho, Samantha, Bonnard, Carine, Hamamy, Hanan, Shboul, Mohammad, Reversade, Bruno, Kayserili, Hülya, Bruneau, Benoit G., Hsiao, Edward C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926823/
https://www.ncbi.nlm.nih.gov/pubmed/27453922
http://dx.doi.org/10.1016/j.bonr.2016.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926823/
https://www.ncbi.nlm.nih.gov/pubmed/27453922
http://dx.doi.org/10.1016/j.bonr.2016.02.005

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