N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation

Osteoclasts are the only cells in an organism capable of resorbing bone. These cells differentiate from monocyte/macrophage lineage cells upon stimulation by receptor activator of NF-κB ligand (RANKL). On the other hand, osteoclastogenesis is reportedly suppressed by glucose via the downregulation o...

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Detalles Bibliográficos
Autores principales: Takeuchi, Tomoharu, Nagasaka, Moyuko, Shimizu, Miyuki, Tamura, Mayumi, Arata, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926832/
https://www.ncbi.nlm.nih.gov/pubmed/28326343
http://dx.doi.org/10.1016/j.bonr.2016.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926832/
https://www.ncbi.nlm.nih.gov/pubmed/28326343
http://dx.doi.org/10.1016/j.bonr.2016.02.001

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