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N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation
Osteoclasts are the only cells in an organism capable of resorbing bone. These cells differentiate from monocyte/macrophage lineage cells upon stimulation by receptor activator of NF-κB ligand (RANKL). On the other hand, osteoclastogenesis is reportedly suppressed by glucose via the downregulation o...
Autores principales: | Takeuchi, Tomoharu, Nagasaka, Moyuko, Shimizu, Miyuki, Tamura, Mayumi, Arata, Yoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926832/ https://www.ncbi.nlm.nih.gov/pubmed/28326343 http://dx.doi.org/10.1016/j.bonr.2016.02.001 |
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