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Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival
As a critical regulator of cell growth, the mechanistic target of rapamycin (mTOR) protein operates as part of two molecularly and functionally distinct complexes. Herein, we demonstrate that mTOR complex molecular composition varies in different somatic tissues. In astrocytes and neural stem cells,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926861/ https://www.ncbi.nlm.nih.gov/pubmed/27340174 http://dx.doi.org/10.1101/gad.279661.116 |