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Evaluation of X Chromosome Inactivation with Respect to HLA Genetic Susceptibility in Rheumatoid Arthritis and Systemic Sclerosis

BACKGROUND: Autoimmune diseases, including rheumatoid arthritis (RA) and systemic sclerosis (SSc) are characterized by a strong genetic susceptibility from the Human Leucocyte Antigen (HLA) locus. Additionally, disorders of epigenetic processes, in particular non-random X chromosome inactivation (XC...

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Detalles Bibliográficos
Autores principales: Kanaan, Sami B., Onat, Onur E., Balandraud, Nathalie, Martin, Gabriel V., Nelson, J. Lee, Azzouz, Doua F., Auger, Isabelle, Arnoux, Fanny, Martin, Marielle, Roudier, Jean, Ozcelik, Tayfun, Lambert, Nathalie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927113/
https://www.ncbi.nlm.nih.gov/pubmed/27355582
http://dx.doi.org/10.1371/journal.pone.0158550