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A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S

Fighting antibiotic resistance requires a deeper understanding of the genetic factors that determine the antibiotic susceptibility of bacteria. Here we describe a chemical-genomic screen in Escherichia coli K-12 that was designed to discover new aspects of antibiotic resistance by focusing on a set...

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Detalles Bibliográficos
Autores principales: Shiver, Anthony L., Osadnik, Hendrik, Kritikos, George, Li, Bo, Krogan, Nevan, Typas, Athanasios, Gross, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927156/
https://www.ncbi.nlm.nih.gov/pubmed/27355376
http://dx.doi.org/10.1371/journal.pgen.1006124