Cargando…

A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S

Fighting antibiotic resistance requires a deeper understanding of the genetic factors that determine the antibiotic susceptibility of bacteria. Here we describe a chemical-genomic screen in Escherichia coli K-12 that was designed to discover new aspects of antibiotic resistance by focusing on a set...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shiver, Anthony L., Osadnik, Hendrik, Kritikos, George, Li, Bo, Krogan, Nevan, Typas, Athanasios, Gross, Carol A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927156/ https://www.ncbi.nlm.nih.gov/pubmed/27355376 http://dx.doi.org/10.1371/journal.pgen.1006124

Ejemplares similares

Correction: A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S
por: Shiver, Anthony L., et al.
Publicado: (2017)

Uptake and transport of antibiotic kasugamycin in castor bean (Ricinus communis L.) seedlings
por: Zhang, Hongzhen, et al.
Publicado: (2022)

Chemical genetics in drug discovery
por: Cacace, Elisabetta, et al.
Publicado: (2017)

Effects of Kasugamycin on the Translatome of Escherichia coli
por: Lange, Christian, et al.
Publicado: (2017)

Insights into the Stress Response Triggered by Kasugamycin in Escherichia coli
por: Müller, Christian, et al.
Publicado: (2016)

The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation
por: Zhang, Yan, et al.
Publicado: (2022)

Alanine-mediated P cycle boosting enhances the killing efficiency of kasugamycin on antibiotic-resistant Xanthomonas oryzae
por: Guan, Yi, et al.
Publicado: (2023)

Inhibitory Activities of Blasticidin S Derivatives on Aflatoxin Production by Aspergillus Flavus
por: Yoshinari, Tomoya, et al.
Publicado: (2017)

KasQ an Epimerase Primes the Biosynthesis of Aminoglycoside Antibiotic Kasugamycin and KasF/H Acetyltransferases Inactivate Its Activity
por: Rattinam, Rajesh, et al.
Publicado: (2022)

The standalone aminopeptidase PepN catalyzes the maturation of blasticidin S from leucylblasticidin S
por: Yu, Guiyang, et al.
Publicado: (2015)

Blasticidin S Deaminase: A New Efficient Selectable Marker for Chlamydomonas reinhardtii
por: de Carpentier, Félix, et al.
Publicado: (2020)

Discovery of Kasugamycin as a Potent Inhibitor of Glycoside Hydrolase Family 18 Chitinases
por: Qi, Huitang, et al.
Publicado: (2021)

The chlamydial functional homolog of KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness
por: Binet, Rachel, et al.
Publicado: (2009)

Transformation of Sexually Transmitted Infection-Causing Serovars of Chlamydia trachomatis Using Blasticidin for Selection
por: Ding, Honglei, et al.
Publicado: (2013)

Blasticidin-S deaminase, a new selection marker for genetic transformation of the diatom Phaeodactylum tricornutum
por: Buck, Jochen M., et al.
Publicado: (2018)

Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA
por: Powers, Kyle T, et al.
Publicado: (2021)

Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation
por: Chaudhuri, Swarnava, et al.
Publicado: (2018)

Phage Cocktail in Combination with Kasugamycin as a Potential Treatment for Fire Blight Caused by Erwinia amylovora
por: Kim, Sang-Guen, et al.
Publicado: (2022)

Guanidine N-methylation by BlsL Is Dependent on Acylation of Beta-amine Arginine in the Biosynthesis of Blasticidin S
por: Wang, Xiankun, et al.
Publicado: (2017)

pSIR-bsr, a self-inactivating retrovirus vector expressing the blasticidin S-resistance gene
por: Fujii, Hodaka
Publicado: (2021)

A tool-kit for high-throughput, quantitative analyses of genetic interactions in E. coli
por: Typas, Athanasios, et al.
Publicado: (2008)

Over expression of the selectable marker blasticidin S deaminase gene is toxic to human keratinocytes and murine BALB/MK cells
por: Bento, Fernanda Mara, et al.
Publicado: (2004)

Discovery and Characterization of BlsE, a Radical S-Adenosyl-L-methionine Decarboxylase Involved in the Blasticidin S Biosynthetic Pathway
por: Feng, Jun, et al.
Publicado: (2013)

Development of a stable transgenic Theileria equi parasite expressing an enhanced green fluorescent protein/blasticidin S deaminase
por: Tuvshintulga, Bumduuren, et al.
Publicado: (2021)

A cotransformation system of the unicellular red alga Cyanidioschyzon merolae with blasticidin S deaminase and chloramphenicol acetyltransferase selectable markers
por: Fujiwara, Takayuki, et al.
Publicado: (2021)

A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism
por: Paradis-Bleau, Catherine, et al.
Publicado: (2014)

Transfection of Babesia bovis by Double Selection with WR99210 and Blasticidin-S and Its Application for Functional Analysis of Thioredoxin Peroxidase-1
por: Asada, Masahito, et al.
Publicado: (2015)

A tool named Iris for versatile high-throughput phenotyping in microorganisms
por: Kritikos, George, et al.
Publicado: (2017)

Learning directed acyclic graphs from large-scale genomics data
por: Nikolay, Fabio, et al.
Publicado: (2017)

Differential network biology
por: Ideker, Trey, et al.
Publicado: (2012)

Mapping genetic interactions in cancer: a road to rational combination therapies
por: Tutuncuoglu, Beril, et al.
Publicado: (2019)

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria
por: Fay, Allison, et al.
Publicado: (2019)

Signals and systems
por: Krogan, Nevan J, et al.
Publicado: (2006)

The next frontier of systems biology: higher-order and interspecies interactions
por: Fischbach, Michael A, et al.
Publicado: (2010)

Creating collaboration by breaking down scientific barriers
por: Fabius, Jacqueline M., et al.
Publicado: (2021)

Lessons learned for pandemic preparedness: A collaborative network is imperative
por: Fabius, Jacqueline M., et al.
Publicado: (2023)

Perceived neighborhood illicit drug selling, peer illicit drug disapproval and illicit drug use among U.S. high school seniors
por: Duncan, Dustin T, et al.
Publicado: (2014)

Towards accurate imputation of quantitative genetic interactions
por: Ulitsky, Igor, et al.
Publicado: (2009)

Illicit : how smugglers, traffickers, and copycats are hijacking the global economy /
por: Naím, Moisés
Publicado: (2006)

Neglected Tropical Diseases, Neglected Data Sources, and Neglected Issues
por: Singer, Burton H., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_s09upg0m4rs1v8se142jtp7jr2