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Targeted Mutagenesis of the Hypophysiotropic Gnrh3 in Zebrafish (Danio rerio) Reveals No Effects on Reproductive Performance

Gnrh is the major neuropeptide regulator of vertebrate reproduction, triggering a cascade of events in the pituitary-gonadal axis that result in reproductive competence. Previous research in mice and humans has demonstrated that Gnrh/GNRH null mutations result in hypogonadotropic hypogonadism and in...

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Detalles Bibliográficos
Autores principales: Spicer, Olivia Smith, Wong, Ten-Tsao, Zmora, Nilli, Zohar, Yonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927163/
https://www.ncbi.nlm.nih.gov/pubmed/27355207
http://dx.doi.org/10.1371/journal.pone.0158141