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Dual function of cTAGE5 in collagen export from the endoplasmic reticulum

Two independent functions of cTAGE5 have been reported in collagen VII export from the endoplasmic reticulum (ER). cTAGE5 not only forms a cargo receptor complex with TANGO1, but it also acts as a scaffold to recruit Sec12, a guanine-nucleotide exchange factor for Sar1 GTPase, to ER exit sites. Howe...

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Detalles Bibliográficos
Autores principales: Tanabe, Tomoya, Maeda, Miharu, Saito, Kota, Katada, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927275/
https://www.ncbi.nlm.nih.gov/pubmed/27170179
http://dx.doi.org/10.1091/mbc.E16-03-0180