Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin

Ubiquilin proteins contain a ubiquitin-like domain (UBL) and ubiquitin-associated domain(s) that interact with the proteasome and ubiquitinated substrates, respectively. Previous work established the link between ubiquilin mutations and neurodegenerative diseases, but the function of ubiquilin prote...

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Detalles Bibliográficos
Autores principales: Chuang, Kun-Han, Liang, Fengshan, Higgins, Ryan, Wang, Yanchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927277/
https://www.ncbi.nlm.nih.gov/pubmed/27170182
http://dx.doi.org/10.1091/mbc.E16-01-0026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927277/
https://www.ncbi.nlm.nih.gov/pubmed/27170182
http://dx.doi.org/10.1091/mbc.E16-01-0026

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