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Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow

Endomitosis is a special type of mitosis in which only cytokinesis—the final step of the cell division cycle—is defective, resulting in polyploid cells. Although endomitosis is biologically important, its regulatory aspects remain elusive. Psychosine, a lysogalactosylceramide, prevents proper cytoki...

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Detalles Bibliográficos
Autores principales: Watanabe, Hiroshi, Okahara, Kyohei, Naito-Matsui, Yuko, Abe, Mitsuhiro, Go, Shinji, Inokuchi, Jinichi, Okazaki, Toshiro, Kobayashi, Toshihide, Kozutsumi, Yasunori, Oka, Shogo, Takematsu, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927278/
https://www.ncbi.nlm.nih.gov/pubmed/27170180
http://dx.doi.org/10.1091/mbc.E15-08-0555