Comparative Analysis of Cas9 Activators Across Multiple Species

Several groups have generated programmable transcription factors based on the versatile Cas9 protein, yet their relative potency and effectiveness across various cell types and species remain unexplored. Here, we compare Cas9 activator systems and examine their ability to induce robust gene expressi...

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Detalles Bibliográficos
Autores principales: Chavez, Alejandro, Tuttle, Marcelle, Pruitt, Benjamin W, Ewen-Campen, Ben, Chari, Raj, Ter-Ovanesyan, Dmitry, Haque, Sabina J, Cecchi, Ryan J, Kowal, Emma J K, Buchthal, Joanna, Housden, Benjamin E, Perrimon, Norbert, Collins, James J, Church, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927356/
https://www.ncbi.nlm.nih.gov/pubmed/27214048
http://dx.doi.org/10.1038/nmeth.3871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927356/
https://www.ncbi.nlm.nih.gov/pubmed/27214048
http://dx.doi.org/10.1038/nmeth.3871

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