A Hybrid Approach for de novo Human Genome Sequence Assembly and Phasing

Despite tremendous progress in genome sequencing, the basic goal of producing phased (haplotype-resolved) genome sequence with end-to-end contiguity for each chromosome at reasonable cost and effort is still unrealized. In this study, we describe a new approach to perform de novo genome assembly and...

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Detalles Bibliográficos
Autores principales: Mostovoy, Yulia, Levy-Sakin, Michal, Lam, Jessica, Lam, Ernest T, Hastie, Alex R, Marks, Patrick, Lee, Joyce, Chu, Catherine, Lin, Chin, Džakula, Željko, Cao, Han, Schlebusch, Stephen A., Giorda, Kristina, Schnall-Levin, Michael, Wall, Jeffrey D., Kwok, Pui-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927370/
https://www.ncbi.nlm.nih.gov/pubmed/27159086
http://dx.doi.org/10.1038/nmeth.3865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927370/
https://www.ncbi.nlm.nih.gov/pubmed/27159086
http://dx.doi.org/10.1038/nmeth.3865

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