DADA2: High resolution sample inference from Illumina amplicon data

We present DADA2, a software package that models and corrects Illumina-sequenced amplicon errors. DADA2 infers sample sequences exactly, without coarse-graining into OTUs, and resolves differences of as little as one nucleotide. In several mock communities DADA2 identified more real variants and out...

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Detalles Bibliográficos
Autores principales: Callahan, Benjamin J, McMurdie, Paul J, Rosen, Michael J, Han, Andrew W, Johnson, Amy Jo A, Holmes, Susan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927377/
https://www.ncbi.nlm.nih.gov/pubmed/27214047
http://dx.doi.org/10.1038/nmeth.3869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927377/
https://www.ncbi.nlm.nih.gov/pubmed/27214047
http://dx.doi.org/10.1038/nmeth.3869

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