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Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer

PURPOSE: The aim of this work was to develop a CAIX-specific nanobody conjugated to IRDye800CW for molecular imaging of pre-invasive breast cancer. PROCEDURES: CAIX-specific nanobodies were selected using a modified phage display technology, conjugated site-specifically to IRDye800CW and evaluated i...

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Detalles Bibliográficos
Autores principales: van Brussel, Aram S. A., Adams, Arthur, Oliveira, Sabrina, Dorresteijn, Bram, El Khattabi, Mohamed, Vermeulen, Jeroen F., van der Wall, Elsken, Mali, Willem P. Th. M., Derksen, Patrick W. B., van Diest, Paul J., van Bergen en Henegouwen, Paul M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927611/
https://www.ncbi.nlm.nih.gov/pubmed/26589824
http://dx.doi.org/10.1007/s11307-015-0909-6