Cargando…

Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer

PURPOSE: The aim of this work was to develop a CAIX-specific nanobody conjugated to IRDye800CW for molecular imaging of pre-invasive breast cancer. PROCEDURES: CAIX-specific nanobodies were selected using a modified phage display technology, conjugated site-specifically to IRDye800CW and evaluated i...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Brussel, Aram S. A., Adams, Arthur, Oliveira, Sabrina, Dorresteijn, Bram, El Khattabi, Mohamed, Vermeulen, Jeroen F., van der Wall, Elsken, Mali, Willem P. Th. M., Derksen, Patrick W. B., van Diest, Paul J., van Bergen en Henegouwen, Paul M. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927611/ https://www.ncbi.nlm.nih.gov/pubmed/26589824 http://dx.doi.org/10.1007/s11307-015-0909-6

Ejemplares similares

Near-Infrared Fluorescence Molecular Imaging of Ductal Carcinoma In Situ with CD44v6-Specific Antibodies in Mice: A Preclinical Study
por: Vermeulen, Jeroen F., et al.
Publicado: (2012)

The potential of hypoxia markers as target for breast molecular imaging – a systematic review and meta-analysis of human marker expression
por: Adams, Arthur, et al.
Publicado: (2013)

Optical imaging of pre-invasive breast cancer with a combination of VHHs targeting CAIX and HER2 increases contrast and facilitates tumour characterization
por: Kijanka, Marta M., et al.
Publicado: (2016)

Immunophenotyping invasive breast cancer: paving the road for molecular imaging
por: Vermeulen, Jeroen F, et al.
Publicado: (2012)

Homogeneous tumor targeting with a single dose of HER2-targeted albumin-binding domain-fused nanobody-drug conjugates results in long-lasting tumor remission in mice
por: Xenaki, Katerina T, et al.
Publicado: (2021)

Dual Targeting of Endothelial and Cancer Cells Potentiates In Vitro Nanobody-Targeted Photodynamic Therapy
por: Mashayekhi, Vida, et al.
Publicado: (2020)

Expression of the RNA Helicase DDX3 and the Hypoxia Response in Breast Cancer
por: Bol, Guus M., et al.
Publicado: (2013)

Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody
por: Zeronian, Matthieu R., et al.
Publicado: (2022)

Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast
por: Kuijper, Arno, et al.
Publicado: (2005)

Differential Expression of Growth Factor Receptors and Membrane-Bound Tumor Markers for Imaging in Male and Female Breast Cancer
por: Vermeulen, Jeroen F., et al.
Publicado: (2013)

A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies
por: Oliveira, Sabrina, et al.
Publicado: (2012)

p53 mutations in classic and pleomorphic invasive lobular carcinoma of the breast
por: Ercan, Cigdem, et al.
Publicado: (2012)

Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots
por: Katrukha, Eugene A., et al.
Publicado: (2017)

Specific tumor targeting and activation of Vγ9Vδ2 T cells by bi-specific nanobodies
por: Stam, Anita, et al.
Publicado: (2014)

Expression of hypoxia-inducible factor-1α and cell cycle proteins in invasive breast cancer are estrogen receptor related
por: Bos, Reinhard, et al.
Publicado: (2004)

Multifaceted Activities of Seven Nanobodies against Complement C4b
por: De la O Becerra, Karla I., et al.
Publicado: (2022)

High affinity nanobodies against human epidermal growth factor receptor selected on cells by E. coli display
por: Salema, Valencio, et al.
Publicado: (2016)

Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session
por: Deken, Marion M., et al.
Publicado: (2020)

EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer
por: van Driel, Pieter B.A.A., et al.
Publicado: (2016)

Pathology of hereditary breast cancer
por: van der Groep, Petra, et al.
Publicado: (2011)

A Nanobody‐on‐Quantum Dot Displacement Assay for Rapid and Sensitive Quantification of the Epidermal Growth Factor Receptor (EGFR)
por: Su, Ruifang, et al.
Publicado: (2022)

Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer
por: Vermeulen, Jeroen F., et al.
Publicado: (2012)

No Amplifications of Hypoxia-Inducible Factor-1α Gene in Invasive Breast Cancer: A Tissue Microarray Study
por: Vleugel, Marije M., et al.
Publicado: (2004)

Facile labelling of an anti-epidermal growth factor receptor Nanobody with (68)Ga via a novel bifunctional desferal chelate for immuno-PET
por: Vosjan, Maria J. W. D., et al.
Publicado: (2011)

Resolving bundled microtubules using anti-tubulin nanobodies
por: Mikhaylova, Marina, et al.
Publicado: (2015)

Eps15: a multifunctional adaptor protein regulating intracellular trafficking
por: van Bergen en Henegouwen, Paul MP
Publicado: (2009)

COMMD1 Promotes pVHL and O(2)-Independent Proteolysis of HIF-1α via HSP90/70
por: van de Sluis, Bart, et al.
Publicado: (2009)

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging
por: de Bruijn, Henriette S., et al.
Publicado: (2020)

Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic
por: Beltrán Hernández, Irati, et al.
Publicado: (2021)

Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
por: Hyseni, Agon, et al.
Publicado: (2011)

Comparison of Different Promoter Methylation Assays in Breast Cancer
por: Suijkerbuijk, Karijn P. M., et al.
Publicado: (2010)

Association and Colocalization of Eps15 with Adaptor Protein-2 and Clathrin
por: van Delft, Sanne, et al.
Publicado: (1997)

Membrane domain formation—a key factor for targeted intracellular drug delivery
por: Popov-Čeleketić, Dušan, et al.
Publicado: (2014)

Copy number changes at 8p11-12 predict adverse clinical outcome and chemo- and radiotherapy response in breast cancer
por: Moelans, Cathy B., et al.
Publicado: (2018)

Antibody or Antibody Fragments: Implications for Molecular Imaging and Targeted Therapy of Solid Tumors
por: Xenaki, Katerina T., et al.
Publicado: (2017)

Prognostic Value of Mitotic Index and Bcl2 Expression in Male Breast Cancer
por: Lacle, Miangela M., et al.
Publicado: (2013)

Nipple Aspirate Fluid at a Glance
por: Patuleia, Susana I. S., et al.
Publicado: (2021)

Expression of Connective Tissue Growth Factor in Male Breast Cancer: Clinicopathologic Correlations and Prognostic Value
por: Lacle, Miangela M., et al.
Publicado: (2015)

Conditional Inactivation of HIF-1 Using Intrabodies
por: Groot, Arjan J., et al.
Publicado: (2008)

Hormone- and HER2-receptor assessment in 33,046 breast cancer patients: a nationwide comparison of positivity rates between pathology laboratories in the Netherlands
por: van Dooijeweert, Carmen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6r6viplv4u5kakhq5a6ara6d1i