Sigma-1 Agonist Binding in the Aging Rat Brain: a MicroPET Study with [(11)C]SA4503

PURPOSE: Sigma-1 receptor ligands modulate the release of several neurotransmitters and intracellular calcium signaling. We examined the binding of a radiolabeled sigma-1 agonist in the aging rat brain with positron emission tomography (PET). PROCEDURES: Time-dependent uptake of [(11)C]SA4503 was me...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Nisha K., Visser, Anniek K. D., Rybczynska, Anna A., Nyakas, Csaba J., Luiten, Paul G. M., Kwizera, Chantal, Sijbesma, Jurgen W. A., Elsinga, Philip H., Ishiwata, Kiichi, Dierckx, Rudi A. J. O., van Waarde, Aren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927617/
https://www.ncbi.nlm.nih.gov/pubmed/26637208
http://dx.doi.org/10.1007/s11307-015-0917-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927617/
https://www.ncbi.nlm.nih.gov/pubmed/26637208
http://dx.doi.org/10.1007/s11307-015-0917-6

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