Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis

Nucleosomes are the smallest structural unit of chromatin, composed of 147 base pairs of DNA wrapped around an octamer of histone proteins. Histone function is mediated by extensive post-translational modification by a myriad of nuclear proteins. These modifications are critical for nuclear integrit...

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Detalles Bibliográficos
Autores principales: Sidoli, Simone, Bhanu, Natarajan V., Karch, Kelly R., Wang, Xiaoshi, Garcia, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927705/
https://www.ncbi.nlm.nih.gov/pubmed/27286567
http://dx.doi.org/10.3791/54112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927705/
https://www.ncbi.nlm.nih.gov/pubmed/27286567
http://dx.doi.org/10.3791/54112

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