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An Efficient Procedure for Removal and Inactivation of Alpha-Synuclein Assemblies from Laboratory Materials

Background: Preformed α-synuclein fibrils seed the aggregation of soluble α-synuclein in cultured cells and in vivo. This, and other findings, has kindled the idea that α-synuclein fibrils possess prion-like properties. Objective: As α-synuclein fibrils should not be considered as innocuous, there i...

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Detalles Bibliográficos
Autores principales: Bousset, Luc, Brundin, Patrik, Böckmann, Anja, Meier, Beat, Melki, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927840/
https://www.ncbi.nlm.nih.gov/pubmed/26639448
http://dx.doi.org/10.3233/JPD-150691