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The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity

Latrepirdine (Dimebon™) has been demonstrated to be a neuroprotective and cognition improving agent in neurodegenerative diseases that feature protein aggregation and deposition, such as Alzheimer’s disease (AD). The accumulation of amyloid-β (Aβ) protein aggregates is a key event in the neurodegene...

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Detalles Bibliográficos
Autores principales: Porter, Tenielle, Bharadwaj, Prashant, Groth, David, Paxman, Adrian, Laws, Simon M., Martins, Ralph N., Verdile, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927897/
https://www.ncbi.nlm.nih.gov/pubmed/26836170
http://dx.doi.org/10.3233/JAD-150790