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DNA damage response and repair data with pharmacological modulators of Tousled

Human Tousled kinase 1 (TLK1) plays an important role in chromatin remodeling, replication, and DNA damage response and repair. TLK1 activity is immediately, but transiently, downregulated after genotoxic insult, and its recovery is important for exit from checkpoint arrest and cell survival after r...

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Detalles Bibliográficos
Autores principales: Timiri Shanmugam, Prakash Srinivasan, Nair, Renjith P., DeBenedetti, Arrigo, Caldito, Gloria, Abreo, Fleurette, Sunavala-Dossabhoy, Gulshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927964/
https://www.ncbi.nlm.nih.gov/pubmed/27408917
http://dx.doi.org/10.1016/j.dib.2016.03.075