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Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation

BACKGROUND: Type I interferons (IFN-α/β) have broad and potent immunoregulatory and antiproliferative activities. However, it is still known whether the dietary flavonoids exhibit their antiviral and anticancer properties by modulating the function of type I IFNs. OBJECTIVE: This study aimed at dete...

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Detalles Bibliográficos
Autores principales: Li, Sheng, Yang, Li-juan, Wang, Ping, He, Yu-jiao, Huang, Jun-mei, Liu, Han-wei, Shen, Xiao-fei, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928072/
https://www.ncbi.nlm.nih.gov/pubmed/27356910
http://dx.doi.org/10.3402/fnr.v60.31288