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Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials

Translation of novel therapies from bench to bedside is hampered by profound disparities between animal and human genetics and physiology. The ability to test for efficacy and cardiotoxicity in a clinically relevant human model system would enable more rapid therapy development. We have developed a...

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Detalles Bibliográficos
Autores principales: Kang, C., Qiao, Y., Li, G., Baechle, K., Camelliti, P., Rentschler, S., Efimov, I. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928074/
https://www.ncbi.nlm.nih.gov/pubmed/27356882
http://dx.doi.org/10.1038/srep28798