Microfluidics-based side view flow chamber reveals tether-to-sling transition in rolling neutrophils

Neutrophils rolling at high shear stress (above 6 dyn/cm(2)) form tethers in the rear and slings in the front. Here, we developed a novel photo-lithographically fabricated, silicone(PDMS)-based side-view flow chamber to dynamically visualize tether and sling formation. Fluorescently membrane-labeled...

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Detalles Bibliográficos
Autores principales: Marki, Alex, Gutierrez, Edgar, Mikulski, Zbigniew, Groisman, Alex, Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928115/
https://www.ncbi.nlm.nih.gov/pubmed/27357741
http://dx.doi.org/10.1038/srep28870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928115/
https://www.ncbi.nlm.nih.gov/pubmed/27357741
http://dx.doi.org/10.1038/srep28870

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