A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice

DNA vaccines are cost-effective to manufacture on a global scale and Tat-based DNA vaccines have yielded protective outcomes in preclinical and clinical models of human immunodeficiency virus (HIV), highlighting the potential of such vaccines. However, Tat-based DNA vaccines have been poorly immunog...

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Detalles Bibliográficos
Autores principales: Tomusange, Khamis, Wijesundara, Danushka, Gummow, Jason, Garrod, Tamsin, Li, Yanrui, Gray, Lachlan, Churchill, Melissa, Grubor-Bauk, Branka, Gowans, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928126/
https://www.ncbi.nlm.nih.gov/pubmed/27358023
http://dx.doi.org/10.1038/srep29131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928126/
https://www.ncbi.nlm.nih.gov/pubmed/27358023
http://dx.doi.org/10.1038/srep29131

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