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Reactive Oxygen Species Limit the Ability of Bone Marrow Stromal Cells to Support Hematopoietic Reconstitution in Aging Mice

Aging of organ and abnormal tissue regeneration are recurrent problems in physiological and pathophysiological conditions. This is most crucial in case of high-turnover tissues, like bone marrow (BM). Using reciprocal transplantation experiments in mouse, we have shown that self-renewal potential of...

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Detalles Bibliográficos
Autores principales: Khatri, Rahul, Krishnan, Shyam, Roy, Sushmita, Chattopadhyay, Saborni, Kumar, Vikash, Mukhopadhyay, Asok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928131/
https://www.ncbi.nlm.nih.gov/pubmed/27140293
http://dx.doi.org/10.1089/scd.2015.0391