Consomic mouse strain selection based on effect size measurement, statistical significance testing and integrated behavioral z-scoring: focus on anxiety-related behavior and locomotion

BACKGROUND: Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently requires the identification of the respective phenotypic trait of interest and is simply based on a significant difference between a con...

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Detalles Bibliográficos
Autores principales: Labots, M., Laarakker, M. C., Ohl, F., van Lith, H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928255/
https://www.ncbi.nlm.nih.gov/pubmed/27357390
http://dx.doi.org/10.1186/s12863-016-0411-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928255/
https://www.ncbi.nlm.nih.gov/pubmed/27357390
http://dx.doi.org/10.1186/s12863-016-0411-4

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