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The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer’s disease

Inflammation is becoming increasingly recognized as an important contributor to Alzheimer’s disease (AD) pathogenesis. As a part of the innate immune system, the complement cascade enhances the body’s ability to destroy and remove pathogens and has recently been shown to influence Alzheimer’s associ...

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Detalles Bibliográficos
Autores principales: Bonham, Luke W., Desikan, Rahul S., Yokoyama, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928261/
https://www.ncbi.nlm.nih.gov/pubmed/27357286
http://dx.doi.org/10.1186/s40478-016-0339-y