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Genomic analysis of nontypeable pneumococci causing invasive pneumococcal disease in South Africa, 2003–2013

BACKGROUND: The capsular polysaccharide is the principal virulence factor of Streptococcus pneumoniae and a target for current pneumococcal vaccines. However, some pathogenic pneumococci are serologically nontypeable [nontypeable pneumococci (NTPn)]. Due to their relative rarity, NTPn are poorly cha...

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Detalles Bibliográficos
Autores principales: Mohale, Thabo, Wolter, Nicole, Allam, Mushal, Ndlangisa, Kedibone, Crowther-Gibson, Penny, du Plessis, Mignon, von Gottberg, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928513/
https://www.ncbi.nlm.nih.gov/pubmed/27334470
http://dx.doi.org/10.1186/s12864-016-2808-x