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The cytotoxicity study of praziquantel enantiomers

Praziquantel (PZQ) is prescribed as a racemic mixture (racemic-PZQ, rac-PZQ), which is composed of (R)-PZQ and (S)-PZQ. In this work, the cytotoxicity of rac-PZQ and its two enantiomers (R)-PZQ and (S)-PZQ on eight cell lines (L-02, HepG2, prf-plc-5, SH-SY5Y, HUVEC, A549, HCT-15, Raw264.7) was evalu...

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Detalles Bibliográficos
Autores principales: Sun, Qian, Mao, Ruifeng, Wang, Dongling, Hu, Changyan, Zheng, Yang, Sun, Dequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928669/
https://www.ncbi.nlm.nih.gov/pubmed/27445457
http://dx.doi.org/10.2147/DDDT.S98096