Cargando…
Acute Stress Responses Are Early Molecular Events of Retinal Degeneration in Abca4(−/−)Rdh8(−/−) Mice After Light Exposure
PURPOSE: Mice lacking ATP-binding cassette transporter 4 (ABCA4) and retinol dehydrogenase 8 (RDH8) mimic features of human Stargardt disease and age-related macular degeneration. RNA-sequencing of whole eyes was done to study early gene expression changes in Abca4(−/−)Rdh8(−/−) mice. METHODS: Abca4...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928696/ https://www.ncbi.nlm.nih.gov/pubmed/27315541 http://dx.doi.org/10.1167/iovs.15-18993 |