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Tools for Early Prediction of Drug Loading in Lipid-Based Formulations

[Image: see text] Identification of the usefulness of lipid-based formulations (LBFs) for delivery of poorly water-soluble drugs is at date mainly experimentally based. In this work we used a diverse drug data set, and more than 2,000 solubility measurements to develop experimental and computational...

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Detalles Bibliográficos
Autores principales: Alskär, Linda C., Porter, Christopher J. H., Bergström, Christel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928820/
https://www.ncbi.nlm.nih.gov/pubmed/26568134
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00704