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Epidermal Growth Factor Receptor Mutation Enhances Expression of Cadherin-5 in Lung Cancer Cells

Epidermal growth factor receptor (EGFR) activation has been shown to play a critical role in tumor angiogenesis. In this study, we investigate the correlation between EGFR mutations and cadherin-5 (CDH5), which is an angiogenic factor, in lung cancer cells. Increased expression CDH5 is observed in l...

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Detalles Bibliográficos
Autores principales: Hung, Ming-Szu, Chen, I-Chuan, Lung, Jr-Hau, Lin, Paul-Yann, Li, Ya-Chin, Tsai, Ying-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928829/
https://www.ncbi.nlm.nih.gov/pubmed/27362942
http://dx.doi.org/10.1371/journal.pone.0158395