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A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations

Meta-analysis of multiple genome-wide association studies (GWAS) has become an effective approach for detecting single nucleotide polymorphism (SNP) associations with complex traits. However, it is difficult to integrate the readily accessible SNP-level summary statistics from a meta-analysis into m...

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Detalles Bibliográficos
Autores principales: Zhang, Han, Wheeler, William, Hyland, Paula L., Yang, Yifan, Shi, Jianxin, Chatterjee, Nilanjan, Yu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928884/
https://www.ncbi.nlm.nih.gov/pubmed/27362418
http://dx.doi.org/10.1371/journal.pgen.1006122