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Dopamine D(1) signaling organizes network dynamics underlying working memory

Local prefrontal dopamine signaling supports working memory by tuning pyramidal neurons to task-relevant stimuli. Enabled by simultaneous positron emission tomography–magnetic resonance imaging (PET-MRI), we determined whether neuromodulatory effects of dopamine scale to the level of cortical networ...

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Detalles Bibliográficos
Autores principales: Roffman, Joshua L., Tanner, Alexandra S., Eryilmaz, Hamdi, Rodriguez-Thompson, Anais, Silverstein, Noah J., Ho, New Fei, Nitenson, Adam Z., Chonde, Daniel B., Greve, Douglas N., Abi-Dargham, Anissa, Buckner, Randy L., Manoach, Dara S., Rosen, Bruce R., Hooker, Jacob M., Catana, Ciprian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928887/
https://www.ncbi.nlm.nih.gov/pubmed/27386561
http://dx.doi.org/10.1126/sciadv.1501672