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Rickettsia australis Activates Inflammasome in Human and Murine Macrophages

Rickettsiae actively escape from vacuoles and replicate free in the cytoplasm of host cells, where inflammasomes survey the invading pathogens. In the present study, we investigated the interactions of Rickettsia australis with the inflammasome in both mouse and human macrophages. R. australis induc...

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Detalles Bibliográficos
Autores principales: Smalley, Claire, Bechelli, Jeremy, Rockx-Brouwer, Dedeke, Saito, Tais, Azar, Sasha R., Ismail, Nahed, Walker, David H., Fang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928923/
https://www.ncbi.nlm.nih.gov/pubmed/27362650
http://dx.doi.org/10.1371/journal.pone.0157231