Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition

The Drosophila neural receptor Dscam1 (Down syndrome cell adhesion molecule 1) plays an essential role in neuronal wiring and self-avoidance. Dscam1 potentially encodes 19,008 ectodomains through alternative RNA splicing and exhibits exquisite isoform-specific homophilic binding, which makes it an e...

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Detalles Bibliográficos
Autores principales: Li, Shu-Ang, Cheng, Linna, Yu, Yamei, Wang, Jia-huai, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928987/
https://www.ncbi.nlm.nih.gov/pubmed/27386517
http://dx.doi.org/10.1126/sciadv.1501118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928987/
https://www.ncbi.nlm.nih.gov/pubmed/27386517
http://dx.doi.org/10.1126/sciadv.1501118

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