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miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis

Pathologic features of idiopathic pulmonary fibrosis (IPF) include genetic predisposition, activation of the unfolded protein response, telomere attrition, and cellular senescence. The mechanisms leading to alveolar epithelial cell (AEC) senescence are poorly understood. MicroRNAs (miRNAs) have been...

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Detalles Bibliográficos
Autores principales: Disayabutr, Supparerk, Kim, Eun Kyung, Cha, Seung-Ick, Green, Gary, Naikawadi, Ram P., Jones, Kirk D., Golden, Jeffrey A., Schroeder, Aaron, Matthay, Michael A., Kukreja, Jasleen, Erle, David J., Collard, Harold R., Wolters, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928999/
https://www.ncbi.nlm.nih.gov/pubmed/27362652
http://dx.doi.org/10.1371/journal.pone.0158367