RNA Polymerase II cluster dynamics predict mRNA output in living cells

Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate clustering with functional consequences in vivo. We developed a live-cell super-resolution approach to uncover the correlation between mRNA synth...

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Detalles Bibliográficos
Autores principales: Cho, Won-Ki, Jayanth, Namrata, English, Brian P, Inoue, Takuma, Andrews, J Owen, Conway, William, Grimm, Jonathan B, Spille, Jan-Hendrik, Lavis, Luke D, Lionnet, Timothée, Cisse, Ibrahim I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929003/
https://www.ncbi.nlm.nih.gov/pubmed/27138339
http://dx.doi.org/10.7554/eLife.13617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929003/
https://www.ncbi.nlm.nih.gov/pubmed/27138339
http://dx.doi.org/10.7554/eLife.13617

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