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A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro

Fusion of mitochondrial outer membranes is crucial for proper organelle function and involves large GTPases called mitofusins. The discrete steps that allow mitochondria to attach to one another and merge their outer membranes are unknown. By combining an in vitro mitochondrial fusion assay with ele...

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Detalles Bibliográficos
Autores principales: Brandt, Tobias, Cavellini, Laetitia, Kühlbrandt, Werner, Cohen, Mickaël M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929004/
https://www.ncbi.nlm.nih.gov/pubmed/27253069
http://dx.doi.org/10.7554/eLife.14618