Mechanisms of modulation of cytokine release by human cord blood monocytes exposed to high concentrations of caffeine

BACKGROUND: Serum caffeine concentrations >20µg/mL (100 µM) in infants treated for apnea of prematurity increases TNF-α and decreases IL-10, change that perhaps is linked to co-morbidities. We hypothesize that this pro-inflammatory cytokine profile may be linked to differential binding of caffein...

Descripción completa

Detalles Bibliográficos
Autores principales: Chavez-Valdez, Raul, Ahlawat, Rajni, Wills-Karp, Marsha, Gauda, Estelle B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929021/
https://www.ncbi.nlm.nih.gov/pubmed/26982450
http://dx.doi.org/10.1038/pr.2016.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929021/
https://www.ncbi.nlm.nih.gov/pubmed/26982450
http://dx.doi.org/10.1038/pr.2016.50

Ejemplares similares