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Mechanisms of modulation of cytokine release by human cord blood monocytes exposed to high concentrations of caffeine
BACKGROUND: Serum caffeine concentrations >20µg/mL (100 µM) in infants treated for apnea of prematurity increases TNF-α and decreases IL-10, change that perhaps is linked to co-morbidities. We hypothesize that this pro-inflammatory cytokine profile may be linked to differential binding of caffein...
Autores principales: | Chavez-Valdez, Raul, Ahlawat, Rajni, Wills-Karp, Marsha, Gauda, Estelle B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929021/ https://www.ncbi.nlm.nih.gov/pubmed/26982450 http://dx.doi.org/10.1038/pr.2016.50 |
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