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TOLUENE DISRUPTION OF THE FUNCTIONS OF L1 CELL ADHESION MOLECULE AT CONCENTRATIONS ASSOCIATED WITH OCCUPATIONAL EXPOSURES

BACKGROUND: Prenatal toluene exposure can cause neurodevelopmental disabilities similar to fetal alcohol syndrome. Both share neuroanatomic pathologies similar to children with mutations in L1 cell adhesion molecule (L1). L1 mediates neurite outgrowth (NOG) via signaling through ERK1/2 which require...

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Detalles Bibliográficos
Autores principales: White, Kimberly M.R., Sabatino, Julia A., He, Min, Davis, Natalie, Tang, Ningfeng, Bearer, Cynthia F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929035/
https://www.ncbi.nlm.nih.gov/pubmed/27027721
http://dx.doi.org/10.1038/pr.2016.40