Aberrant Promoter Methylation at CpG Cytosines Induce the Upregulation of the E2F5 Gene in Breast Cancer

PURPOSE: The promoter methylation status of cell cycle regulatory genes plays a crucial role in the regulation of the eukaryotic cell cycle. CpG cytosines are actively subjected to methylation during tumorigenesis, resulting in gain/loss of function. E2F5 gene has growth repressive activities; vario...

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Detalles Bibliográficos
Autores principales: Ali, Arshad, Ullah, Farman, Ali, Irum Sabir, Faraz, Ahmad, Khan, Mumtaz, Shah, Syed Tahir Ali, Ali, Nawab, Saeed, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929253/
https://www.ncbi.nlm.nih.gov/pubmed/27382388
http://dx.doi.org/10.4048/jbc.2016.19.2.133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929253/
https://www.ncbi.nlm.nih.gov/pubmed/27382388
http://dx.doi.org/10.4048/jbc.2016.19.2.133

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