MEAN inhibits hepatitis C virus replication by interfering with a polypyrimidine tract‐binding protein

MEAN (6‐methoxyethylamino‐numonafide) is a small molecule compound, and here, we report that it effectively inhibits hepatitis C virus (HCV) infection in an HCV cell culture system using a JC1‐Luc chimeric virus, with a 50% effective concentration (EC50) of 2.36 ± 0.29 μM. Drug combination usage ana...

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Detalles Bibliográficos
Autores principales: Xue, Jihua, Liu, Yanning, Yang, Ying, Wu, Shanshan, Hu, Ying, Yang, Fan, Zhou, Xiaotang, Wang, Jing, Chen, Feng, Zheng, Min, Zhu, Haihong, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929307/
https://www.ncbi.nlm.nih.gov/pubmed/26929148
http://dx.doi.org/10.1111/jcmm.12798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929307/
https://www.ncbi.nlm.nih.gov/pubmed/26929148
http://dx.doi.org/10.1111/jcmm.12798

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