Telomere and Telomerase Therapeutics in Cancer

Telomerase is a reverse transcriptase capable of utilizing an integrated RNA component as a template to add protective tandem telomeric single strand DNA repeats, TTAGGG, to the ends of chromosomes. Telomere dysfunction and telomerase reactivation are observed in approximately 90% of human cancers;...

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Detalles Bibliográficos
Autores principales: Xu, Yucheng, Goldkorn, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929421/
https://www.ncbi.nlm.nih.gov/pubmed/27240403
http://dx.doi.org/10.3390/genes7060022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929421/
https://www.ncbi.nlm.nih.gov/pubmed/27240403
http://dx.doi.org/10.3390/genes7060022

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